A predicted site in selenoprotein P (SELENOP, Figure 2C) is at position 56, 3 residues prior to the first selenocysteine, such that cleavage here would likely interfere with the N-terminal redox activity, possibly without affecting the Se-transport function of the rest of the protein
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Although the treated mice did not develop more skin tumors than similar mice that had not been fed the antioxidants, they developed twice as many tumors in their lymph nodes, a hallmark of the spread of cancera process called metastasis